Scientific Meeting and Workshop

Life Sciences campus, Buildings A and Basic Fit, Vrije Universiteit Brussel
Laarbeeklaan 103, 1090 Brussels, Belgium

21 November 2019 – SYMPOSIUM
“Innovative tools for 3Rs testing”
9:00 Registration and welcome coffee (Building A)
Session 1 – Chairperson: Vera Rogiers
9:30 Welcome on behalf of the presidents of Invitrom, IC-3Rs & BelTox
Peter in’t Veld, Dean Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel (VUB), BE
9:45 Regulatory risk assessment today and tomorrow: the role of non-animal testing
Vera Rogiers, Innovative Centre 3Rs (IC-3Rs), Vrije Universiteit Brussel (VUB), BE
10:15 In silico approaches in risk assessment: application of read-across and QSARs in a tiered testing strategy
Andrew Worth, Joint Research Centre (JRC), IT
11:00 Coffee break (Building A)
Session 2 – Chairperson: Arno Gutleb
11:30 Status of in vitro methods in risk assessment
Anne Kienhuis, Rijksinstituut voor Volksgezondheid en Milieu (RIVM), NL
12:15 Use of 3D models and organ-on-a-chip for pharmaceutical testing
Stefan Przyborski (Durham University), GB
13:00-13:30 BelTox General Assembly – INVITROM General Assembly
locations of these meetings will be communicated by the session chairperson
13:00 Lunch and poster viewing (Basic Fit)
Session 3 – Chairperson: Nynke Kramer
14:45 Use of alternative approaches in ecotoxicology
Lucia Vergauwen, Universiteit Antwerpen (UA), BE
15:30 Young Scientist presentations
15h30 – 15h45
Development of an in vitro model for the identification of respiratory sensitizers
Aline Chary, LIST

15h45 – 16h00
3D neurons model for studying neurodegenerative disorders
Rania Aro, University of Mons

16h00 – 16h15
Growth factors of the stem cell niche to improve the viability of precision-cut intestinal slices
Carin Biel, University of Groningen

16h15 – 16h30
A complex 3D tetra-culture alveolar in vitro model to study the acute toxicological effects of gold nanoparticle suspensions
Melissa Saibene, LIST

16:30 Use of artificial intelligence in toxicology and risk assessment
Timothy Allen, Cambridge University, GB
17:15 Proclamation of the winners of the young scientist presentation contest
22 November 2019 – WORKSHOP
“Designing research projects according to the 3Rs”
10:00-16:00 A case study: Experimental design, statistics, 3R-information, databanks, ethical committee, biobanking, …
Workshop is limited to 50 attendants (no inscription fee, can only be followed when attending the Symposium)
10:00-10:10 Introduction
Vera Rogiers, IC-3Rs, VUB
10:10-10:50 Case study on DILI based on experimental animals
Leo Van Grunsven, VUB
10:55-11:35 Study design and statistics
Kurt Barbé
11:35-12:10 Coffee break
12:10-12:30 Search for relevant data
Sandrine Vandenput, Université de Liège
12:35-12:55 In silico methodology
Steve Gutsell, Unilever, UK
13:00-14:00 Lunch
14:05-14:25 In vitro models for DILI
Joost Boeckmans, VUB
14:30-14:50 Ethical commission experimental animals/human samples
Joery De Kock, VUB
14:55-15:15 Biobank
Johan Guns, VUB
15:20-15:35 DMP
Carole Urlings, VUB
15:40-15:55 Open Access
Lucy Ames, VUB
Closure of workshop

Organizing committee:

Mathieu Vinken (BelTox)
Joost Boeckmans (Invitrom)
Vera Rogiers (IC-3Rs/VUB)

Flyer Joint symposium IC-BT-IV 2019