Advance Course

Genotoxicity & mutagenicity testing: a brief overview of the main tests, pitfalls and regulatory framework

Elewijt (Elewijt center), 11 October 2013

Organised by BelTox and BEMS

 

9:00
 
Welcome
9:10-9:20
 
General introduction. Genotoxicity testing at the right position in hazard evaluation
Peter Hoet & Lode Godderis (KU Leuven, BelTox & Bems)
 
9:20-10:15

 

Background & mechanisms
Lode Godderis (KU Leuven)

10:15-10:45
 
          Break (Coffee & thee)
 
10:45-11:30
 
Genotoxicity testing: an introduction to the different test systems
Ilse Koijen / Bas-jan van der Leede (Janssen R&D)

11:30-12:00
 
Regulatory aspects (EMA & ICH)
Sonja Beken (FAMHP)

12:00-13:00
 
          Lunch
 
13:00-13:30
 
TTC concept in genetic toxicology
Jacky van Gompel (Janssen R&D)

13:30-14:00
 
False positives and strategies of testing
Philippe Vanparys (Altoxicon Bvba)

14:00-14:15
 
Exercise / case study: introduction & questions to solve
Ilse Koijen / Bas-jan van der Leede (Janssen R&D)

14:15-16:00
 
Exercise / case study: study in subgroups
expert assistance
coffee and thee available
16:00-16:30
 
Interactive overview of the cases
(comparing/discussing outcomes per group)

16:30
 
Final remarks and adjournments

 

Organizing committee:
BEMS: Lode Godderis, Freddy Van Goethem –
BelTox: Philip Vanparys, Peter Hoet

To download, use the attachment at the bottom of this page.

Itinerary:

The Elewijt Center informed us that it is very likely there will be roadworks on the regular route to the center.
It is expected that, although there is a barrier, local traffic will be allowed.
If not, please use the alternative itinerary in the attachment at the bottom of this page.